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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ca3b45e88425da087fbd1357cad96619d8b8bf75ad8c48d81d7c1f821b9049e' 
  AND token = 'bYWo2cM5hdUFyeT+rnBGfSfLmEymg8Ov43HRg+97X1A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}