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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '67c188fa52e7bb39024443b3416d2024ea8e1140a47ee92850f35ee99f6c29af' 
  AND token = 'ICgewWYwUPKBwygDCq4U4ocrKlJholxr2yeR8eNrClo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}