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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'afaa1cff9e2e53190f53efee4dc660545b23e5786083939b77fb12d34c562d81' 
  AND token = 'TY0+W4yU6rXeZHsY7EA7Up1hK71emuupZ7lMJl/93KE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}