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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8fe9bad81b33dde4a9cc4dc445c37868c52a6875dddd2487a0fc8f95941b5654' 
  AND token = 'kAvpF2nAQJ29E4wTgrRSN0aSAQ5HG71RosWtjnUZLVE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}