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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a72ec9daf5760513b5bffbcccd05b0084c7201f162229bc88365b9224d14e97' 
  AND token = 'ChHraZQ2sMjbhjBQabhFEyjALoQoiONNF3R/Y49c40A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}