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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b472826f965e783a243bed9a5a9ed0fdf6cb171947172a1c671bee1a7ee31e6' 
  AND token = '8mZbwO89r3wqI6fMJ7fABNOImNv5UV/c5snTkrcZak4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}