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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '248d59c39fb3c8d57ec6648a2c1b9af234391d77cc26ee9fd02cdf4f2d192f2c' 
  AND token = 'SB3VNnzTl1Z4RT4YTBABiTa2MIMQGe7ODmms90By0QA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}