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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21084efd71ef0d85409241ddac6813df632a2b738459b3a8d4e13b0ce563b844' 
  AND token = 'AC+2vBgC0VlJrnRvwJ2yF82m4gb7cuBMjzp4C1fMqB8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}