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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5680131aa76c1949d98c2565810d8a5aad2d7e51e0b1ff0506233af2ea156733' 
  AND token = 'x1WkGnfVOlzcuEFjJ2R4diMOQZOt2bRc/X4XbcFJ3eA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}