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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12725aa4c65144cbcaf5adef4660a0d37da4e79ce99088bac2d6a674d92017cc' 
  AND token = 'ykAv1dD7vhyxQCkAL+EkT8/borefBrVAB2xaRcwVoas=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}