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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9cbd5f2da47f76fe35542d93bb4cc64d929e34b89cfe490f275e81bb9c25423a' 
  AND token = 'kQLpln+EkvewyLuPAdWiL9sx74cb9TgGlFhZRl6ZEJo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}