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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05ffa0167cfd0e2241279d09b53845c8d101e891f5617590a7dd83e293cc018a' 
  AND token = '9sYe7QitQa9QyDpHlRgZVV8GEmOC8RsdrsO+GKGVN5o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}