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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8efe75a67818288d9767961d7a39558940882cc4d8e66c0572509fe17acda23' 
  AND token = 'XnYwSW1oURATi+BZDMx8g20WtWQQpyRQwj4ovhOw14U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}