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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44573346fd9903586e1d9f17286a68edc0111c689c7839da792f984a1b088e3a' 
  AND token = 'yxAk0ATsK/R1+yNn2ar8O1V5HIG+CKknyshabNxn+ns=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}