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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff0e602011c90caeb4ae9fa434f76a03e757957e1a8da9b1989abc208f4afdfa' 
  AND token = 'vL7vhBc/9VEgrH1U5Sj9eIfqCUJJqhmLZW2NGHpHGvk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}