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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4af57febb368f41a4734c2f466118fc6e7429178aa0e8e1928b02a0e03b51ce0' 
  AND token = 'DX6Ze9y9Cz0QzPgnpuVlxxYAnfhimun0Ek1pCt5EPwA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}