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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1a4c600220ef2b8f2dfe0deb8c224edd057596a8ec8a7e4d8be184c13331d8f' 
  AND token = 'jAuLdXev3n2vzWwKCXJju6R/+576RXY0VnLw8OwS+Gw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}