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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b6903e9fa99febc918a1422db9008f37600607902b4fc550c7a54e9bb12fb8f5' 
  AND token = 'ALKlN39dBFy0YLWdTA3zTK8iNuygW7K2kXvuh1kZPIw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}