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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a22410e6f8f12e029b5731558a60cd7be2bf258828168395e5c8f62c65e61a8' 
  AND token = 'Ff21z0xegp38zX4VEvCTB70WYdnab6xRpY9uNDWwqbI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}