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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f77fd834a83aa01e8844e451355fbb0d9c38227bab78957bf2ab8ea24d562c18' 
  AND token = 'cHT/eCNDgXhwtr110Jlq9IG2bQpo1B8Es1NdnCCRF34=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}