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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9be33e9c43d18384eb66b9f96acbdd3a0d7e6b46ce3e5ee15812a72c68540704' 
  AND token = 'us4DEZ238f5f7HjWi4oWdf5XZc8s/LUS1atHH7gyo5s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}