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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce72b93705ee1a355e97ff12fe34edd827f2279be43b64324126c8e39a18f846' 
  AND token = 'nFyXMozV4s5D6ywQQU8Bi2vuMsK726mDPPeTxOJY3Is=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}