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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c21a62fce77e9d5bf6375e909d664637833f4f4543fefda0a563f22e42493c25' 
  AND token = 'BY3qyf9yD87/gCMqZrEflAPU1k4BPLIphcKYgDgEi18=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}