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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '327506173a2e30828ed441569570b5cdff6fa62a7f58b402dde8f6d400f593eb' 
  AND token = 'S72ZlycCGtuMHVDVUxYz7buXNEHH0bWSxQOFzuZSTZ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}