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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6820408daf7f382e6e41ba034bea9e0f5c1e75716e3e5c0b694358da6217962' 
  AND token = '+5ZjujskpU14QeQIHjmmpMQuWv1LvF3bTvJyAlYaYZg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}