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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81ddec76d13b5e78d0ec788a3b8bfcf111f14bb31a33f6c376fba1147b2d0bb5' 
  AND token = 'LJPu3X7l6KqTBgyzgq89twjq5EbpxVx/JNh1hBTMheA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}