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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd4d08a285c0479f64457fa6437fe060b678d6ac57b776e080b1cb315375308e7' 
  AND token = 'mDifTh+sMhHa27AAygZudmQOXDB6v2B2n+zh5q4LOg8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}