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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '022d40bf7e4ac5ff736819d56e4d3ecf73c6f8c3562547fc9c85ba9c0246e9d5' 
  AND token = 'kdHoCi55Sxz7TrGmLB1eL+sgAQlSvPKzMZXKK28pKcQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}