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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14c6aa4060c14bd118e96aedfdee2dd55296eb173e024310e031d0416448c613' 
  AND token = 'gnqx5WpvTGtYdT8sv+Mr6eRCi5IhuuYnAexWbDMNbJE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}