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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '61ca297760a3ea44e9a91134cb9401eb5c5fe084856dd3ee05fbfb89ab748818' 
  AND token = 'dt1i7FCPCsGYn2AQNC6Cdmn7++xgYOA3l7oEkpzMbdo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}