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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a5ee9c3ea2f57729d0d3d0bba088d6bcfe51009d2e28d69b7cc66e9585de4f9' 
  AND token = 'EdOka2IuHmE5f4sGKoZhH3CPMZA68jcBLKGJQ7b7E0A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}