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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a6f80b78dcc02fc6e5f5a9c0d28e4b5ef63534b7af638c5ab9431a7ac09e20b' 
  AND token = '5Xt7EvlFdn6r9kI4mGPJTyCGVLdR7AGWniAcrZQ1Qxs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}