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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1512b7ab536105b04a8a36e7d7c84279fbcb5f63216a052ef6120d3841900fcf' 
  AND token = 'lN80T2qW1mrvx3qYYirKs6aDRGUALj80/DWhxTz0Tgw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}