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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88bb77a77b949d59791142f32aef2c451cf9e173024008ef933f252c836f9620' 
  AND token = 'KTwZzN4LEdNV3gIhc5YJneIbZE2F3P7S1Njosd+0VIo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}