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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd2b20e32a960350e3557997c773246f0d4c1136a024f46b63aa39ad3c91264c7' 
  AND token = '2EzCKfJa/miDhFRHUwzJaOxE8CcI6zmGFBdC/mrfgxg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}