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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f1a3e7f536c8d4b05e044eb2ea519806dd51329b5b7c8e035d0b51d976c6d38' 
  AND token = 'S+anY/2K41bDPZe8A5BXxOOiNVV/eWyYzfLVrIXB2T0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}