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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd2861072159dd51b5fe24dd2b692ed928885430b65a5db1881accba41f2be73d' 
  AND token = 'k2gphL6LZ92dN+E4KN6khInf96pvYN0912k9abW1Sgw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}