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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3993ed970977812d23bbbe3fb13e0640304da40fb4086ef44ae58c355940cc9d' 
  AND token = 'I4Uo8hPInX2t/9sO4F+6vxIiNsFvcyg8QAr8VtnGBMw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}