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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b509d35c896b1edb5681deea837899ecde8348f0727679f0d131b22fb9a8749' 
  AND token = 'lPmMFHKicCo/eCqtU71FGkMZ0iv9nGLoUe1TW3Opd4M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}