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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d90ed2287cc4a247460325c1fa6c2e7780af0b3dc24babc11a7ae1e3bb50a5f' 
  AND token = 'EJGfjmxZcYscQ6RSqmVL/rhb08nFJN9C+OO2P0OUYz0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}