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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00a2efd6a8dbb8006f545f54f83a0215d8bbc8f97705370e84c527cc94449008' 
  AND token = 'tIuiFwKC23xFjd9NbklZYx4CXqkCh9wEBeeUDZnurR0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}