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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'acd4ca2b5fd566653211a3ba0412e27e6ab1c60b0de1890da931cb38c71f2891' 
  AND token = 'c5sv4prGASF6TjutiKg5yyB3r5hX4tzQOUeMP9r1xLY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}