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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ecf350484bc09941f082fb2e30450b6e889ce0f79d3a244dcc818599be4dd54' 
  AND token = '7maMhFzZirpEaP9g1wu8oOg6OD9OtYdGhEQ4v8aJJFs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}