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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a58e62820a0177c33b1eaadd91ce7baeb6a4930b3a9a792d1e8424cbb6720d0' 
  AND token = '4N5t4AO+ilXbj0iPQXHQNToGGRlfkoVeJ36lQHq10jw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}