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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '09a8bbf97c2b342dbff48a963de7d8f72423a0af8bc92d71ffad64c7553f74a5' 
  AND token = 'yeX8oxNf/mN3/riC0jI3xFyR8+ahHs2Kxd6VT0sPOuc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}