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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c488539e0e911f17bfe3d3b2fdc16beb42aca738ceb8e48623d66dc072fa8c30' 
  AND token = 'mSmCtJNEHk73JgkNEnWzkwU/MhB2nPckpw0si+pBEHM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}