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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a5aa1820d7d65ce26ad36a418f20325cb93679babce6ad9d68c1f06d00bcfb8' 
  AND token = '5UudQdvojl9TNXEifpj2krDl9CdlLDSD+Nkjl2+bnE4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}