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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b74eff770453fd66d31b14fb53f14300b0270288423d3381edc7e96b0a1ee02' 
  AND token = 'NTB6ZNQa12KiIU25D5PnlR+3ZA13hm4vVPGXLyBpiAo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}