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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b9b91164d905a5242c14b07232f5904c4fa4dda5fd584b4db800c84b79462d5' 
  AND token = 'NA0XGpbDjgTKgZLV01KGgEIOpo2s+Nxm2FKbBKrhz7E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}