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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b06f5e182fe90ff6b7147456e03709245d93002ba57a909c4a9c3b94b72ca13d' 
  AND token = 'wHgDtFHHT2pybvVT8VG+DVcnC7E2U8V1e5TLHj0TV9Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}